Compare the Top Package Managers that integrate with Python as of October 2025

This a list of Package Managers that integrate with Python. Use the filters on the left to add additional filters for products that have integrations with Python. View the products that work with Python in the table below.

What are Package Managers for Python?

Package managers are software tools that automate the process of installing, upgrading, configuring, and removing software packages. They simplify dependency management by ensuring that required libraries and modules are downloaded and updated correctly. Many package managers connect to online repositories, allowing developers and system administrators to access large ecosystems of software quickly. By standardizing installations and updates, they reduce errors, improve consistency, and save time in both development and production environments. Package managers are widely used across programming languages, operating systems, and frameworks to streamline software distribution and maintenance. Compare and read user reviews of the best Package Managers for Python currently available using the table below. This list is updated regularly.

  • 1
    AWS CodeArtifact
    Store and share artifacts across accounts, with appropriate levels of access granted to your teams and build systems. Reduce overhead from setup and maintenance of an artifact server or infrastructure with a fully managed service. Only pay for software packages stored, number of requests made, and data transferred out of Region with pay-as-you-go pricing. Configure CodeArtifact to fetch from public repositories such as the npm Registry, Maven Central, Python Package Index (PyPI), and NuGet. Securely share private packages across organizations by publishing them to a central organizational repository. Build automated approval workflows with CodeArtifact APIs and Amazon EventBridge, with visibility into your packages using AWS CloudTrail. Pull dependencies from CodeArtifact in AWS CodeBuild and publish new versions of your private packages secured with AWS Identity and Access Management (IAM).
    Starting Price: $0.05 per GB per month
  • 2
    PyPI

    PyPI

    PyPI

    PyPI is the official repository for Python software packages, hosting hundreds of thousands of projects that developers can publish and users can discover and install. It supports both source distributions (“sdists”) and pre-built binary “wheels”, allowing packages to include native extensions for different platforms. Projects on PyPI consist of multiple releases, each of which can include various files for different operating systems or Python versions. Metadata for each package includes things like version number, dependencies, licensing, classifiers, description (including rendering Markdown or reStructuredText), and other information that tools like pip use to resolve, download, and install the correct package. PyPI provides search and filtering based on package metadata, letting users find what they need via keywords, compatibility, or other package attributes.
    Starting Price: Free
  • 3
    Flox

    Flox

    Flox

    Flox is a development environment manager and package tool that lets developers define, share, and replicate consistent environments across machines by leveraging the Nix ecosystem. Flox lets you create environments via a simple manifest.toml, layering and replacing dependencies precisely where needed. It activates subshells with reproducible dependencies and integrates shell hooks, version constraints, and services (e.g., local databases) to automate setup. Because it runs on the host system (rather than inside containers), developers maintain access to files, configurations, SSH keys, and shell aliases without Docker-style bind mounts. Flox supports cross-platform and multi-architecture environments by default, allowing environments to run identically on various systems; you can constrain them to specific systems or use package groups to manage architecture-specific dependencies.
    Starting Price: $20 per month
  • 4
    Google Cloud Artifact Registry
    Artifact Registry is Google Cloud’s unified, fully managed package and container registry designed for high-performance artifact storage and dependency management. It centralizes host­ing of container images (Docker/OCI), Helm charts, language packages (Java/Maven, Node.js/npm, Python), and OS packages, offering fast, scalable, reliable, and secure handling with built-in vulnerability scanning and IAM-based access control. Integrated seamlessly with Google Cloud CI/CD tools like Cloud Build, Cloud Run, GKE, Compute Engine, and App Engine, it supports regional and virtual repositories with granular security via VPC Service Controls and customer-managed encryption keys. Developers benefit from standardized Docker Registry API support, comprehensive REST/RPC interfaces, and migration paths from Container Registry. Daily updated documentation includes quickstarts, repository management, access configuration, observability tools, and deep-dive guides.
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