diff --git a/include/proxy-wasm/exports.h b/include/proxy-wasm/exports.h
index 15305a2ad..7fe8a4c57 100644
--- a/include/proxy-wasm/exports.h
+++ b/include/proxy-wasm/exports.h
@@ -74,12 +74,12 @@ template <typename Pairs> size_t pairsSize(const Pairs &result) {
 
 template <typename Pairs> void marshalPairs(const Pairs &result, char *buffer) {
   char *b = buffer;
-  *reinterpret_cast<uint32_t *>(b) = result.size();
+  *reinterpret_cast<uint32_t *>(b) = htole32(result.size());
   b += sizeof(uint32_t);
   for (auto &p : result) {
-    *reinterpret_cast<uint32_t *>(b) = p.first.size();
+    *reinterpret_cast<uint32_t *>(b) = htole32(p.first.size());
     b += sizeof(uint32_t);
-    *reinterpret_cast<uint32_t *>(b) = p.second.size();
+    *reinterpret_cast<uint32_t *>(b) = htole32(p.second.size());
     b += sizeof(uint32_t);
   }
   for (auto &p : result) {
diff --git a/include/proxy-wasm/word.h b/include/proxy-wasm/word.h
index e96fdfb94..549968342 100644
--- a/include/proxy-wasm/word.h
+++ b/include/proxy-wasm/word.h
@@ -17,6 +17,11 @@
 
 #include <iostream>
 
+#ifdef __APPLE__
+#define htole32(x) (x)
+#define le32toh(x) (x)
+#endif
+
 namespace proxy_wasm {
 
 #include "proxy_wasm_common.h"
diff --git a/src/exports.cc b/src/exports.cc
index 673fd1fe9..3e4f2622f 100644
--- a/src/exports.cc
+++ b/src/exports.cc
@@ -64,16 +64,16 @@ Pairs toPairs(std::string_view buffer) {
   if (buffer.size() < sizeof(uint32_t)) {
     return {};
   }
-  auto size = *reinterpret_cast<const uint32_t *>(b);
+  auto size = le32toh(*reinterpret_cast<const uint32_t *>(b));
   b += sizeof(uint32_t);
   if (sizeof(uint32_t) + size * 2 * sizeof(uint32_t) > buffer.size()) {
     return {};
   }
   result.resize(size);
   for (uint32_t i = 0; i < size; i++) {
-    result[i].first = std::string_view(nullptr, *reinterpret_cast<const uint32_t *>(b));
+    result[i].first = std::string_view(nullptr, le32toh(*reinterpret_cast<const uint32_t *>(b)));
     b += sizeof(uint32_t);
-    result[i].second = std::string_view(nullptr, *reinterpret_cast<const uint32_t *>(b));
+    result[i].second = std::string_view(nullptr, le32toh(*reinterpret_cast<const uint32_t *>(b)));
     b += sizeof(uint32_t);
   }
   for (auto &p : result) {
@@ -712,7 +712,8 @@ Word writevImpl(Word fd, Word iovs, Word iovs_len, Word *nwritten_ptr) {
     }
     const uint32_t *iovec = reinterpret_cast<const uint32_t *>(memslice.value().data());
     if (iovec[1] /* buf_len */) {
-      memslice = context->wasmVm()->getMemory(iovec[0] /* buf */, iovec[1] /* buf_len */);
+      memslice = context->wasmVm()->getMemory(le32toh(iovec[0]) /* buf */,
+                                              le32toh(iovec[1]) /* buf_len */);
       if (!memslice) {
         return 21; // __WASI_EFAULT
       }
diff --git a/src/v8/v8.cc b/src/v8/v8.cc
index 29f3de090..057c364ca 100644
--- a/src/v8/v8.cc
+++ b/src/v8/v8.cc
@@ -432,7 +432,7 @@ bool V8::getWord(uint64_t pointer, Word *word) {
   }
   uint32_t word32;
   ::memcpy(&word32, memory_->data() + pointer, size);
-  word->u64_ = word32;
+  word->u64_ = le32toh(word32);
   return true;
 }
 
@@ -441,7 +441,7 @@ bool V8::setWord(uint64_t pointer, Word word) {
   if (pointer + size > memory_->data_size()) {
     return false;
   }
-  uint32_t word32 = word.u32();
+  uint32_t word32 = htole32(word.u32());
   ::memcpy(memory_->data() + pointer, &word32, size);
   return true;
 }
diff --git a/src/wamr/wamr.cc b/src/wamr/wamr.cc
index 590de6823..de9cee494 100644
--- a/src/wamr/wamr.cc
+++ b/src/wamr/wamr.cc
@@ -340,7 +340,7 @@ bool Wamr::getWord(uint64_t pointer, Word *word) {
 
   uint32_t word32;
   ::memcpy(&word32, wasm_memory_data(memory_.get()) + pointer, size);
-  word->u64_ = word32;
+  word->u64_ = le32toh(word32);
   return true;
 }
 
@@ -349,7 +349,7 @@ bool Wamr::setWord(uint64_t pointer, Word word) {
   if (pointer + size > wasm_memory_data_size(memory_.get())) {
     return false;
   }
-  uint32_t word32 = word.u32();
+  uint32_t word32 = htole32(word.u32());
   ::memcpy(wasm_memory_data(memory_.get()) + pointer, &word32, size);
   return true;
 }
diff --git a/src/wasmtime/wasmtime.cc b/src/wasmtime/wasmtime.cc
index 8bef920a6..ef47f7d39 100644
--- a/src/wasmtime/wasmtime.cc
+++ b/src/wasmtime/wasmtime.cc
@@ -354,7 +354,7 @@ bool Wasmtime::getWord(uint64_t pointer, Word *word) {
 
   uint32_t word32;
   ::memcpy(&word32, wasm_memory_data(memory_.get()) + pointer, size);
-  word->u64_ = word32;
+  word->u64_ = le32toh(word32);
   return true;
 }
 
@@ -363,7 +363,7 @@ bool Wasmtime::setWord(uint64_t pointer, Word word) {
   if (pointer + size > wasm_memory_data_size(memory_.get())) {
     return false;
   }
-  uint32_t word32 = word.u32();
+  uint32_t word32 = htole32(word.u32());
   ::memcpy(wasm_memory_data(memory_.get()) + pointer, &word32, size);
   return true;
 }
diff --git a/src/wavm/wavm.cc b/src/wavm/wavm.cc
index 1b0d7383c..e7bbcf040 100644
--- a/src/wavm/wavm.cc
+++ b/src/wavm/wavm.cc
@@ -344,12 +344,12 @@ bool Wavm::getWord(uint64_t pointer, Word *data) {
   auto p = reinterpret_cast<char *>(memory_base_ + pointer);
   uint32_t data32;
   memcpy(&data32, p, sizeof(uint32_t));
-  data->u64_ = data32;
+  data->u64_ = le32toh(data32);
   return true;
 }
 
 bool Wavm::setWord(uint64_t pointer, Word data) {
-  uint32_t data32 = data.u32();
+  uint32_t data32 = htole32(data.u32());
   return setMemory(pointer, sizeof(uint32_t), &data32);
 }
 
diff --git a/test/runtime_test.cc b/test/runtime_test.cc
index 7bfd39211..d741919a9 100644
--- a/test/runtime_test.cc
+++ b/test/runtime_test.cc
@@ -56,7 +56,7 @@ TEST_P(TestVM, Memory) {
   ASSERT_TRUE(vm_->getWord(0x2000, &word));
   ASSERT_EQ(100, word.u64_);
 
-  int32_t data[2] = {-1, 200};
+  uint32_t data[2] = {htole32(static_cast<uint32_t>(-1)), htole32(200)};
   ASSERT_TRUE(vm_->setMemory(0x200, sizeof(int32_t) * 2, static_cast<void *>(data)));
   ASSERT_TRUE(vm_->getWord(0x200, &word));
   ASSERT_EQ(-1, static_cast<int32_t>(word.u64_));