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What if AI could help people with Major Depressive Disorder
Why AI Could Change Depression Treatment, But Hasn’t Yet. The Promise of AI in Mental Health Care.
In August 2025, my colleagues and I published a systematic review on Machine learning approaches in the therapeutic outcome prediction in major depressive disorder: a systematic review. in Frontiers Psychiatry
Artificial Intelligence — AI, has become one of the most discussed technologies in modern healthcare. From diagnosing diseases to analysing medical images, AI is often presented as a tool capable of transforming medicine. But when it came to major depressive disorder (MDD), can machine learning actually help doctors choose the right treatment for the right patient?
That was our question. Could AI predict the outcome of a therapy for a particular patient way before they started their treatment? In other words, what role does AI play in personalised treatment?
Just like for cancer treatments, patients are first tested for the exact type of cancer they have before starting treatment. Nobody really goes in blind.
WHY DOES IT MATTER?
MDD affects hundreds of millions of people worldwide. Despite decades of research, predicting whether a patient will respond to a particular treatment remains a challenge. Many…
