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        <title><![CDATA[Stories by Mahsa Hosseini on Medium]]></title>
        <description><![CDATA[Stories by Mahsa Hosseini on Medium]]></description>
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            <title>Stories by Mahsa Hosseini on Medium</title>
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            <title><![CDATA[Dopamine Says Go, Amygdala Says Wait]]></title>
            <link>https://medium.com/@mahhosseini0081/dopamine-says-go-amygdala-says-wait-f8d2c1929cfa?source=rss-2b34bcb60189------2</link>
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            <category><![CDATA[neuroscience]]></category>
            <category><![CDATA[self-improvement]]></category>
            <category><![CDATA[evolutionary-psychology]]></category>
            <category><![CDATA[brain]]></category>
            <category><![CDATA[dopamine]]></category>
            <dc:creator><![CDATA[Mahsa Hosseini]]></dc:creator>
            <pubDate>Mon, 04 May 2026 09:58:08 GMT</pubDate>
            <atom:updated>2026-05-04T14:50:12.617Z</atom:updated>
            <content:encoded><![CDATA[<p><em>Midnight casts its shadow over the room. The lights are off; only the cold glow of the laptop lights your face. Five years of nonstop work, a résumé you’ve rewritten over and over, and now a single “Send” button stands between you and your dream of studying on the other side of the world. You feel joy boiling in your veins. But in that same second, an old voice rises inside your head: “What if I send it and get rejected? What if I get excited too soon and everything falls apart?”</em></p><figure><img alt="" src="https://cdn-images-1.medium.com/max/1024/1*rCgRtX3KkcuNsy_0t_jt4A.png" /></figure><h3>• Why is the brain suspicious of joy?</h3><p>As always, the story begins with evolution. In the distant past, during long days filled with struggle and running for survival, if our ancestors had taken intense joy as a sign that &quot;everything is fine,&quot; their attention would have drifted away from the nearby bushes. The cost of such a mistake was likely a surprise attack by a saber‑toothed tiger hiding behind those very bushes. That is why our neural circuits are built on the principle of &quot;better a false alarm than fatal neglect.&quot; In other words, there are always rules in the brain that warn us: joy may be allowed, but it must not be so loud that it silences the alarm bells.</p><p>Inside the wiring of neurons, two main engines are at work: the reward axis (VTA → nucleus accumbens) and the threat axis (amygdala → hypothalamus). When life gives us a small taste of success (for example, an invitation to a job interview or news of a salary increase), the VTA (ventral tegmental area) releases dopamine at full power, splashing it all over the brain. At the same time, the amygdala, which is evolutionarily older, pulls that same signal under a spotlight and whispers: &quot;How do we know there isn&#39;t danger hiding somewhere?&quot; The key point is that these two production lines never evolved to work together; each has its own history, and the modern human brain, is forced to mediate between them.</p><h3>• The Other Side of Reward Prediction Error</h3><p>In the late 1990s, Wolfram Schultz placed electrodes in the brains of macaque monkeys and showed that dopamine responds precisely to the difference between &quot;what is expected&quot; and &quot;what actually happens.&quot; If a reward arrives on time, dopamine spikes at the moment of prediction; if it doesn&#39;t arrive or is less than expected, dopamine drops sharply and the animal quickly shows signs of stress. This is called the &quot;Reward Prediction Error&quot;. Now imagine how the human brain acts to lower the risk of such a drop (that bitter feeling of disappointment). It&#39;s simple: it lowers your expectations or even drafts a detailed scenario of failure so that the upcoming blow, however small, feels softer. In other words, the anxiety that grips us before joy is, in practice, a kind of preventive vaccine, not a curse from the universe.</p><h3>• Hedonic Adaptation: Why “Eternal Happiness” Is a Myth</h3><p>But sometimes the story goes even beyond anticipating painful disappointment. If pain can last in the mind, why doesn&#39;t joy stay just as stable? To answer this, we have to turn to a classic study: in 1978, researchers named Brickman, Coates, and Janoff-Bulman tracked Illinois state lottery winners for six months. Their wave of euphoria was strong in the first weeks, but it didn&#39;t take more than six months for their happiness curve to return to baseline. No sudden disaster had occurred, nor was the world at war with them. The secret lies simply in a brain phenomenon called Hedonic Adaptation. In this &quot;adaptation to pleasure,&quot; the brain, in order to stay in control of behavior and function, brings excessively high happiness back to a normal level over time, so that focus, motivation, and sleep aren&#39;t sacrificed to excitement. So the decline of pleasure is the result of a regulatory mechanism, not a flaw in our fate.</p><h3>• Why a Tiger Matters More Than an Apple?</h3><p>Although modern humans no longer face saber‑toothed tigers, the “negativity bias” still rules the brain’s warning systems. Research by Kahneman and Tversky in behavioral economics showed that losses weigh two to three times more than equal gains in decision‑making. Brain imaging studies using fMRI have also confirmed that amygdala activity in response to possible threats is stronger than the nucleus accumbens’ response to an equal reward. So if you feel that, during events, the shadow of anxiety is larger than the joy itself, you are not wrong; this is the hardwired design of our neural software.</p><h3>• So what should we do?</h3><p>Science suggests that instead of suppressing this ancient system, we should tame it with a kind of working contract:</p><p>1. <strong>Affect labeling:</strong> Lieberman&#39;s experiments show that when we describe an emotion with precise words (for example, &quot;a mild warmth at the back of the neck&quot;), the lateral prefrontal cortex filters the amygdala&#39;s negative signal.</p><p>2. <strong>Small rewards:</strong> The Huberman group showed that small, repeated doses of dopamine keep motivation stable without triggering the threat circuitry. So don&#39;t tie joy to &quot;the final result.&quot; The joy of sending your résumé doesn&#39;t need to be postponed for months. Celebrate being alive with a good cup of coffee; after that, celebrate an interview invitation with a pleasant evening walk.</p><p>3. <strong>A written backup plan:</strong> Browning&#39;s study on anticipatory anxiety showed that in stressful situations, having a clear &quot;what if things don&#39;t go my way?&quot; scenario reduces activity in the stress-related prefrontal network. In other words, when the black hole becomes transparent, it is no longer an endless void, and the brain finally accepts that it can simply be stepped over.</p><p>In the end, joy without anxiety is a beautiful dream, but the Homo sapiens brain is wired with the protocol: &quot;a false alarm is better than an unforeseen catastrophe.&quot; The pessimistic voice inside your head is not a problem to be solved; it is an employee in the brain’s security department, in charge of limiting excess risk. Give it tools (affect labeling, small rewards, and a backup plan). Then press &quot;Send&quot; with ease. Dopamine and the amygdala will both do their jobs. You can enjoy the moment without hiding your smile, and if an emergency landing is needed, you will land with minimal turbulence.</p><img src="https://medium.com/_/stat?event=post.clientViewed&referrerSource=full_rss&postId=f8d2c1929cfa" width="1" height="1" alt="">]]></content:encoded>
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