Ardo Sanjaya·Jun 21Understanding Pseudobulking in Single Cell: Why 10,000 cells is sometimes just N = 6A few months ago, my students were analyzing single-cell data comparing non-alcoholic steatohepatitis against a normal liver. The reasoning…
Elliot Xie·Jun 18The Long Tail of Slow Bioinformatics Software, and an Agent Built to Fix ItMany bioinformatics functions become everyday infrastructure long before anyone has time to make them fast.
Jonathan Alles·Nov 3, 2025Single‑Cell Genomics 101: Technologies and workflowsBy EVOBYTE Your partner in bioinformatics
The PrePrint·Oct 2, 2025When Genomes Go RogueWhat can an inventive new methodology and an a party-animal parasite tell us about cancer and aging?
Wei hung Pan·Aug 26, 2025Same Data, Different Story: cell annotation in single-cell sequencingSingle-cell RNA-seq offers a more precise view than bulk RNA-seq because it measures transcripts in individual cells rather than averaging…A response icon1A response icon1
Andres Gutierrez·Jun 20, 2025When the Immune System Shuts Down Blood: A Real-Time Look Inside the Bone MarrowWhat happens when your body forgets that your own cells are yours?
Nardesdirce·Apr 19, 2025Improving Cell Identification in Biology: How AI Consensus Boosts AccuracyIdentifying cell types in complex biological data is crucial but challenging. A new computational approach uses multiple AI language models…
Shivang Sharma·Sep 22, 2024Generalized version of PCA and when to use itDisclaimer: This article discusses GLM-PCA with applications in single-cell RNA sequencing (scRNA-seq). Code snippets are written in R
Yang-Hong Dai·Jul 11, 2024ScRNA for exploring heterogeneity of innate NK cellsPaper reading-nature immunology
