Open Source Free Pascal Medical Software

SimulAdren is a simulation program for the hypothalamus-pituitary-adrenal axis (HPA feedback control). It is based on a nonlinear MiMe-NoCoDI model and uses the CyberUnits Bricks class library.

SimThyr is a continuous simulation program for the human pituitary-thyroid feedback control system. Applications of this program cover research, including development of hypotheses, and education of students in biology and medicine, nurses and patients.

SimulaBeta is a simulation program for insulin-glucose feedback control. It is based on a nonlinear MiMe-NoCoDI model.

SPINA is software for the rapid, reliable and accurate determination of constant structure parameters of endocrine feedback control systems. It is a class of static function tests that require nothing more than steady-state concentrations of hormones or metabolites obtained in vivo. The first version of this cybernetic approach had been developed for the evaluation of the functional status of the thyroid gland, i.e. thyroid's secretory capacity (gain of thyroid, GT or SPINA-GT) and sum activity of peripheral deiodinases (GD or SPINA-GD). A second version has been established for insulin-glucose homeostasis. It delivers the secretory capacity of pancreatic beta cells (SPINA-GBeta), an estimate for the insulin receptor amplification (SPINA-GR) and a static disposition index as a measure for the loop gain of the feedback loop (SPINA-DI). Both implementations of SPINA have been validated in more than 50 clinical studies based on large cohorts.

BMI Wizard calculates the body mass index (BMI) from weight and size and vice versa.

CIMA is a program that provides an easy way to calculate a diversity of body indexes related to the fat content and energy needs, providing a way to control our weight: 1 - Body Mass Index (BMI), including both the traditional and the new proposed formulas, and provides a classification of the results. The evaluation takes in account the age groups (adults, children and the elderly). 2 - Body Adiposity Index (BAI). 3 - Basal Metabolic Rate (BMR) for Men and for Women. 4 - Body Fat Percentage (BFP). 5 - Total Daily Calories Needs based on the activity levels of the user lifestyle. The program supports 3 languages (English, European Portuguese and Brazilian Portuguese). IMPORTANT: CIMA works only with the International System of Units (SI). No other systems are allowed since SI is the standard one. CIMA may still require a depuration before becoming a mature program, but it is already functional and may be downloaded by anyone.

Collection of algorithms for computational statistics in life sciences

Tempomat is software that supports statistical analysis of time series in the life sciences.

Calculator software helping to determine L-T4 and L-T3 substitution dosage according to the algorithms provided by the European Thyroid Association (ETA).