The cell membrane, also known as the plasma membrane, is the thin outer boundary that surrounds the cell and separates it from the external environment. It is composed mainly of lipids and proteins and acts as a semipermeable membrane, allowing only certain substances to enter or leave the cell.

Structure of Cell Membrane
- The cell membrane is mainly composed of a phospholipid bilayer along with proteins, carbohydrates, and cholesterol.
- Phospholipids are arranged in two layers: The hydrophilic heads face the outer and inner watery environments, and the hydrophobic tails face inward toward each other
- This arrangement forms a stable barrier between the cell and its surroundings.
- The phospholipid bilayer prevents free passage of large or charged molecules such as proteins, nucleic acids, and ions.
Characteristics of Cell Membrane
- Thin and flexible structure.
- Made mainly of lipids and proteins.
- Selectively permeable in nature.
- Present in all living cells.
- Maintains the shape and integrity of the cell.
- Participates in transport and cell signalling.
Fluid Mosaic Model
The structure of the cell membrane is explained by the Fluid Mosaic Model, proposed by Singer and Nicolson (1972). According to this model:
- The membrane is fluid in nature
- Proteins float within the lipid bilayer like a mosaic
- Lipids and proteins can move laterally within the membrane
This fluidity allows flexibility and proper functioning of the membrane.
Components of the Cell Membrane
1. Phospholipids
Phospholipids are the main structural components of the membrane, which form the lipid bilayer and provide flexibility and create a selectively permeable barrier.
2. Proteins
- Integral Membrane Proteins: These proteins are embedded within the membrane and may pass completely through it. Transport of substances, cell signalling and acting as receptors are the functions performed by integral membrane proteins. Examples include carrier proteins and channel proteins.
- Peripheral Membrane Proteins: These proteins are loosely attached to the membrane surface by weak interactions such as hydrogen bonds. Structural support, Enzyme activity and Cell communication are the functions performed by peripheral membrane proteins.
3. Cholesterol
Cholesterol is present mainly in animal cell membranes. Maintaining membrane fluidity and preventing the membrane from becoming too rigid or too fluid are the functions of cholesterol.
4. Carbohydrates
Carbohydrates are attached to proteins and lipids on the outer surface of the membrane. Cell recognition, cell communication, and the formation of glycoproteins and glycolipids are the functions performed by carbohydrates.
Functions of the Cell Membrane
- Protects the internal contents of the cell and separates the cell from the external environment.
- Controls the movement of substances such as water, nutrients, gases, and waste products.
- Membrane proteins act as receptors for chemical signals.
- Provides support and maintains the shape of the cell.
- Endocytosis: The process by which the cell takes in substances by engulfing them.
- Exocytosis: The process by which substances are released outside the cell through vesicles.