Real-Time Health Monitoring Solutions

🧬 Your Skin Is a Sensor. This Wearable Reads It—No Contact Needed. A new Nature Portfolio study introduces a non-contact wearable that captures molecular fluxes from the skin in real time—tracking water vapor, VOCs, CO₂, and even the absorption of environmental chemicals. 📍 What it does: Forms a microchamber just above the skin—no adhesive, no irritation. Wireless sensors inside detect how molecules move in and out, revealing physiological and environmental signals with clinical-grade precision. 💨 What are VOCs? Volatile Organic Compounds are vapors released from the skin via: • Microbial activity (e.g. hygiene, odor, dysbiosis) • Inflammation and wound healing • UV-triggered oxidative stress • Uptake of airborne chemicals like ethanol or solvents VOC spikes preceded wound infections, revealed poor hygiene, and increased after UV exposure—correlating with oxidative DNA damage. CO₂ flux reflected metabolic stress. Inward ethanol flux measured chemical absorption through the skin. 💡 Why this matters: The skin is not just a barrier—it’s a real-time interface with the environment. This wearable turns it into a window on whole-body physiology. 🌍 Implications far beyond dermatology: ✅ Critical care: Monitor hydration and tissue integrity in neonates and ICU patients ✅ Respiratory health: CO₂ flux as a non-invasive proxy for arterial CO₂—no need for bulky equipment ✅ Wound care: Track inflammation, healing progress, and infection without disrupting dressings ✅ Occupational safety: Quantify skin absorption of industrial solvents and pollutants ✅ Metabolic monitoring: VOCs and CO₂ patterns could flag systemic conditions before symptoms appear ✅ Environmental research: Real-time exposome data from the skin itself 💡 The device weighs just 11g, runs wirelessly for 24+ hours, and operates without touching fragile skin—ideal for vulnerable populations and long-term monitoring. 📖 Nature, 2025: https://lnkd.in/eRCqAJbY #biotech #wearables #healthtech #exposome #noninvasive #VOC #CO2monitoring #woundcare #pollutionmonitoring #criticalcare #skinbiosensor #molecularhealth #beautybiotech #metabolichealth

MIT researchers just introduced the world’s first wearable device for real-time, continuous monitoring of circulating cells at single-cell resolution! Current methods like blood draws and in vivo flow cytometry offer only intermittent snapshots, often missing critical treatment windows for cancer and cellular therapies. 𝗖𝗶𝗿𝗰𝗧𝗿𝗲𝗸 𝗲𝗻𝗮𝗯𝗹𝗲𝘀 𝗰𝗼𝗻𝘀𝘁𝗮𝗻𝘁, 𝘀𝗶𝗻𝗴𝗹𝗲-𝗰𝗲𝗹𝗹 𝗱𝗲𝘁𝗲𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗹𝗮𝗯𝗲𝗹𝗲𝗱 𝗰𝗶𝗿𝗰𝘂𝗹𝗮𝘁𝗶𝗻𝗴 𝗰𝗲𝗹𝗹𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗮 𝗰𝗼𝗺𝗽𝗮𝗰𝘁, 𝘀𝗺𝗮𝗿𝘁𝘄𝗮𝘁𝗰𝗵-𝘀𝗶𝘇𝗲𝗱 𝗱𝗲𝘃𝗶𝗰𝗲.  1. Achieved reliable detection of single circulating cells under a 400 μm skin phantom with an average SNR of 11.9.  2. Enabled real-time tracking of flowing fluorescent cells at physiological speeds up to 5 mm/s, validated through confocal microscopy.  3. Integrated all electronics into a 44 mm × 39 mm × 15.5 mm package, using focused, pulsed laser excitation and dual SiPM detectors to suppress noise and false positives.  4. Demonstrated safety through Monte Carlo and heat transfer simulations, with maximum skin temperature rise limited to 1.51°C which is well below tissue damage thresholds. Couple thoughts:  • I like that the authors performed Monte Carlo light-transport and heat-transfer simulations validated on porcine skin to ensure safety to skin  • Could replacing the SiPM+analog filters with an integrated CMOS photonics chip and digital signal processing on the ESP32 to further shrink size and power?  • Embedding microfluidic channels in future versions might enable simultaneous cell sorting or multiplexed marker analysis on the wrist Here's the awesome work: https://lnkd.in/gvjDYeju Congrats to Kyuho Jang, Shivam Kajale, Baju C Joy, David Bono, Brian Neltner & Deblina Sarkar! I post my takes on the latest developments in health AI – 𝗰𝗼𝗻𝗻𝗲𝗰𝘁 𝘄𝗶𝘁𝗵 𝗺𝗲 𝘁𝗼 𝘀𝘁𝗮𝘆 𝘂𝗽𝗱𝗮𝘁𝗲𝗱! Also, check out my health AI blog here: https://lnkd.in/g3nrQFxW

🏥 Google's Pixel 3 Will Revolutionize Health Monitoring 🫀 In a groundbreaking development, Google’s Pixel Watch 3 has received clearance from the FDA for its innovative Loss of Pulse Detection feature. This first-of-its-kind technology can detect when a user experiences a loss of pulse and automatically prompt a call to EMS if the user is unresponsive. The feature utilizes the watch’s heart rate sensor. An AI-based algorithm then analyzes signals alongside motion data to confirm a loss of pulse event. If no response or movement is detected, the watch initiates an audio alarm and countdown before contacting EMS. The announcement of the FDA approval corresponds with the publication of a Nature paper this week that validated this algorithm with high specificity in clinical and real-world testing. Nature paper: https://lnkd.in/gUX6Ucua This advancement is key given that out-of-hospital cardiac arrests account for over 356,000 deaths annually in the U.S., with more than half occurring without a witness. By enabling the Pixel Watch 3 to act as a monitor, users can receive timely medical intervention, even when alone, potentially saving lives during critical moments. The Loss of Pulse Detection feature has been available in 14 European countries since September 2024 and is set to roll out to U.S. devices at the end of March 2025. This development showcases Google’s commitment to integrating advanced health monitoring capabilities into everyday wearable technology, bridging the gap between consumer electronics and medical-grade devices. More from Google https://lnkd.in/gWrx6PQe #healthcare #HealthIT #technology #Future Karen DeSalvo @MDHowell

Wearable Devices Can Predict IBD Flares. A groundbreaking study published in Gastroenterology demonstrates that wearable devices can identify and predict inflammatory bowel disease (IBD) flares up to 7 weeks in advance—offering a game-changing approach to chronic disease management. 🩺 Study Overview: Researchers at Mount Sinai Health System’s Icahn School of Medicine conducted a prospective, observational study involving 309 participants across 36 U.S. states diagnosed with Crohn’s disease (CD) or ulcerative colitis (UC). Participants wore Apple Watches (n=255), Fitbits (n=53), and ŌURA Rings (n=16) to passively track key physiological metrics: ✅ Heart Rate (HR) ✅ Resting Heart Rate (RHR) ✅ Heart Rate Variability (HRV) ✅ Daily Step Count ✅ Blood Oxygenation (SpO₂) 💡 Key Findings: 🔹 Circadian patterns of HRV significantly changed between flare and remission periods. 🔹 HR & RHR increased, and step counts decreased during inflammatory and symptomatic flares. 🔹 HR, RHR, HRV, steps, and oxygenation levels changed up to 7 weeks before flare-ups—providing an early warning system for patients and clinicians. 🔹 Wearables could differentiate between symptoms caused by inflammation vs. general discomfort, improving flare detection accuracy. 🚀 Why This Matters: This study marks a major step forward in integrating wearable tech into chronic disease management. With passive, real-time monitoring, IBD patients may soon receive early alerts, enabling proactive intervention, medication adjustments, or lifestyle changes before symptoms escalate. 📢 The Future of Digital Health: Imagine a world where your smartwatch notifies you weeks before a health condition worsens. This is not science fiction—it’s happening now. 💬 What are your thoughts on wearables revolutionizing chronic disease monitoring? Let me know your thoughts below! 👇 🙏 Thank you Shyamal Patel for originally sharing the research. #DigitalHealth #Wearables #IBD #AIinHealthcare #HealthTech #PersonalizedMedicine #Fitness #Wellness #Healthcare

Proton Intelligence Unveils Implantable ‘Wearable’ for Continuous Potassium Monitoring for Kidney and Heart Health> 🫘People with Chronic Kidney Disease (CKD) or at risk of Heart Failure face life-threatening potassium imbalances. While glucose monitors have revolutionized diabetes care, potassium monitoring remains in its early stages 🫘Proton is developing a small device inserted under the skin that connects to a smartphone app, allowing patients to monitor potassium levels in real-time and receive alerts if levels move out of a safe range due to diet or medication 🫘A clinician dashboard will display patients’ potassium trends, enabling care teams to analyze the data and adjust therapies accordingly 🫘It’s an important issue - CKD affects 10% of the global population, with thousands dying annually due to lack of affordable treatment 🫘Competitors like AliveCor (cardiac-based estimates), Alio (dialysis monitoring), and Renalyse (finger-prick tests) have made strides in potassium monitoring. Proton, however, claims its implantable device offers unmatched scalability, usability, and accuracy 🫘Proton just closed a $6.95 million seed round and clinical trials are underway for the product, which is due to launch in 2025 👇Link to article in comments #DigitalHealth #CKD

Small Language Models + Edge Technology = A New Era in #Healthcare AI is revolutionizing healthcare, but it’s not just about large-scale systems. Small Language Models (#SLMs) on edge devices—like smartphones, wearables, and IoT sensors—are creating real-time, cost-effective solutions that transform patient care. These lightweight, localized AI models operate independently of the cloud, ensuring speed, affordability, and security—even in areas with limited connectivity. Here are four powerful ways SLMs on edge devices are already shaping the future of healthcare: 1️⃣ MedAide: Real-Time Diagnostics on Edge Devices Built for low-latency performance, MedAide delivers diagnostic support in remote areas or during emergencies. Think high-quality healthcare anywhere—without relying on robust infrastructure. 2️⃣ CLAID: Unlocking Digital Biomarkers CLAID processes sensor data from wearables and smartphones, enabling real-time monitoring of health metrics (heart rate, oxygen levels, movement). It empowers precision medicine and early condition detection like never before. 3️⃣ Abridge: AI-Powered Medical Transcriptions By summarizing patient-doctor interactions in real time, Abridge saves doctors hours on documentation. Less admin work, more patient care. 4️⃣ AliveCor: AI-Driven Cardiac Monitoring Portable ECG devices that track and analyze heart health in real time. FDA-approved and built for proactive care—whether at home or on the go. Why SLMs on Edge Devices Matter • Speed: No cloud dependency = faster processing. • Cost-Effective: Affordable solutions for wide-scale deployment. • Privacy-First: Localized data processing enhances security. The Future is Now From rural clinics to urban hospitals, SLMs are bridging healthcare gaps, driving efficiency, and saving lives. 💡 Are you ready to integrate AI into your practice? Let’s discuss how small language models and edge tech can enhance workflows, improve care, and shape the future of medicine. #HealthcareInnovation #ArtificialIntelligence #EdgeComputing #HealthTech #DigitalTransformation #DrGPT