Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
Building academic-industry partnerships to improve the relevance and real-world impact of 3Rs models and technologies.
3Rs Prize winning paper addresses poorly performing antibodies to improve reproducibility and drive the uptake of animal-free alternatives.
Over 3,000 members of the public took part in NC3Rs events and activities last year to learn about the 3Rs.
The most recent webinar series from The Togeth3R Consortium was watched by 3,231 people from across the world. If you were not able to attend, the recordings of the talks are available.
A new publication in Nature Communications outlines a tool to check whether sex has been considered when designing and assessing in vivo research proposals.
ECVAM will provide expert advice in validating alternative safety assessment methods, helping to bridge the gap between innovation and market adoption.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
