Clinical Information and Decision Making

Bridging Data Silos in Oncology with Modular Software for Federated Analysis on Fast Healthcare Interoperability Resources: Multisite Implementation Study

Jasmin Ziegler, Marcel Pascal Erpenbeck, Timo Fuchs, Anna Saibold, Paul-Christian Volkmer, Guenter Schmidt, Johanna Eicher, Peter Pallaoro, Renata De Souza Falguera, Fabio Aubele, Marlien Hagedorn, Ekaterina Vansovich, Johannes Raffler, Stephan Ringshandl, Alexander Kerscher, Julia Karolin Maurer, Brigitte Kühnel, Gerhard Schenkirsch, Marvin Kampf, Lorenz A Kapsner, Hadieh Ghanbarian, Helmut Spengler, Iñaki Soto-Rey, Fady Albashiti, Dirk Hellwig, Maximilian Ertl, Georg Fette, Detlef Kraska, Martin Boeker, Hans-Ulrich Prokosch, Christian Gulden

J Med Internet Res 2025 (Apr 15); 27:e65681

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Impact of an Alert-Based Inpatient Clinical Decision Support Tool to Prevent Drug-Induced Long QT Syndrome: Large-Scale, System-Wide Observational Study

Katy E Trinkley, Steven T Simon, Michael A Rosenberg

J Med Internet Res 2025 (Apr 14); 27:e68256

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Identifying Intersecting Factors Associated With Suicidal Thoughts and Behaviors Among Transgender and Gender Diverse Adults: Preliminary Conditional Inference Tree Analysis

Amelia M Stanton, Lauren A Trichtinger, Norik Kirakosian, Simon M Li, Katherine E Kabel, Kiyan Irani, Alexandra H Bettis, Conall O’Cleirigh, Richard T Liu, Qimin Liu

J Med Internet Res 2025 (Apr 11); 27:e65452

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Implementation of an Integrated, Clinical Decision Support Tool at the Point of Antihypertensive Medication Refill Request to Improve Hypertension Management: Controlled Pre-Post Study

John Charles Matulis 3rd, Jason Greenwood, Michele Eberle, Benjamin Anderson, David Blair, Rajeev Chaudhry

JMIR Med Inform 2025 (Apr 11); 13:e70752

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Ethical Design of Data-Driven Decision Support Tools for Improving Cancer Care: Embedded Ethics Review of the 4D PICTURE Project

Marieke Bak, Laura Hartman, Charlotte Graafland, Ida J Korfage, Alena Buyx, Maartje Schermer, 4D PICTURE Consortium

JMIR Cancer 2025 (Apr 10); 11:e65566

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Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Mahmudur Rahman, Jifan Gao, Kyle A Carey, Dana P Edelson, Askar Afshar, John W Garrett, Guanhua Chen, Majid Afshar, Matthew M Churpek

JMIR AI 2025 (Apr 10); 4:e67144

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Web-Based Explainable Machine Learning-Based Drug Surveillance for Predicting Sunitinib- and Sorafenib-Associated Thyroid Dysfunction: Model Development and Validation Study

Fan-Ying Chan, Yi-En Ku, Wen-Nung Lie, Hsiang-Yin Chen

JMIR Form Res 2025 (Apr 10); 9:e67767

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Early Detection of Elevated Ketone Bodies in Type 1 Diabetes Using Insulin and Glucose Dynamics Across Age Groups: Model Development Study

Simon Cichosz, Clara Bender

JMIR Diabetes 2025 (Apr 10); 10:e67867

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Bridging Data Gaps in Emergency Care: The NIGHTINGALE Project and the Future of AI in Mass Casualty Management

The NIGHTINGALE Consortium, Marta Caviglia

J Med Internet Res 2025 (Apr 10); 27:e67318

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A Risk Prediction Model (CMC-AKIX) for Postoperative Acute Kidney Injury Using Machine Learning: Algorithm Development and Validation

Ji Won Min, Jae-Hong Min, Se-Hyun Chang, Byung Ha Chung, Eun Sil Koh, Young Soo Kim, Hyung Wook Kim, Tae Hyun Ban, Seok Joon Shin, In Young Choi, Hye Eun Yoon

J Med Internet Res 2025 (Apr 09); 27:e62853

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Developing a Machine Learning Model for Predicting 30-Day Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Noncardiac Surgery: Retrospective Study

Ju-Seung Kwun, Houng-Beom Ahn, Si-Hyuck Kang, Sooyoung Yoo, Seok Kim, Wongeun Song, Junho Hyun, Ji Seon Oh, Gakyoung Baek, Jung-Won Suh

J Med Internet Res 2025 (Apr 09); 27:e66366

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Digital Decision Support for Perioperative Care of Patients With Type 2 Diabetes: A Call to Action

Jianwen Cai, Peiyi Li, Weimin Li, Xuechao Hao, Sheyu Li, Tao Zhu

JMIR Diabetes 2025 (Apr 08); 10:e70475

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Comparing Random Survival Forests and Cox Regression for Nonresponders to Neoadjuvant Chemotherapy Among Patients With Breast Cancer: Multicenter Retrospective Cohort Study

Yudi Jin, Min Zhao, Tong Su, Yanjia Fan, Zubin Ouyang, Fajin Lv

J Med Internet Res 2025 (Apr 08); 27:e69864

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Model-Based Feature Extraction and Classification for Parkinson Disease Screening Using Gait Analysis: Development and Validation Study

Ming De Lim, Tee Connie, Michael Kah Ong Goh, Nor ‘Izzati Saedon

JMIR Aging 2025 (Apr 08); 8:e65629

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Clinical Benefits and Risks of Antiamyloid Antibodies in Sporadic Alzheimer Disease: Systematic Review and Network Meta-Analysis With a Web Application

Danko Jeremic, Juan D Navarro-Lopez, Lydia Jimenez-Diaz

J Med Internet Res 2025 (Apr 07); 27:e68454

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Investigating Clinicians’ Intentions and Influencing Factors for Using an Intelligence-Enabled Diagnostic Clinical Decision Support System in Health Care Systems: Cross-Sectional Survey

Rui Zheng, Xiao Jiang, Li Shen, Tianrui He, Mengting Ji, Xingyi Li, Guangjun Yu

J Med Internet Res 2025 (Apr 07); 27:e62732

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Development of a Predictive Dashboard With Prescriptive Decision Support for Falls Prevention in Residential Aged Care: User-Centered Design Approach

S Sandun Malpriya Silva, Nasir Wabe, Amy D Nguyen, Karla Seaman, Guogui Huang, Laura Dodds, Isabelle Meulenbroeks, Crisostomo Ibarra Mercado, Johanna I Westbrook

JMIR Aging 2025 (Apr 07); 8:e63609

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Psychological Factors Influencing Appropriate Reliance on AI-enabled Clinical Decision Support Systems: Experimental Web-Based Study Among Dermatologists

Alisa Küper, Georg Christian Lodde, Elisabeth Livingstone, Dirk Schadendorf, Nicole Krämer

J Med Internet Res 2025 (Apr 04); 27:e58660

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Virtual Patients Using Large Language Models: Scalable, Contextualized Simulation of Clinician-Patient Dialogue With Feedback

David A Cook, Joshua Overgaard, V Shane Pankratz, Guilherme Del Fiol, Chris A Aakre

J Med Internet Res 2025 (Apr 04); 27:e68486

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Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025 (Apr 03); 14:e60471

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