Colourized microscopy images of cells of the malaria parasite

Comparative 3D ultrastructure of Plasmodium falciparum gametocytes

Felix Evers et al. use high-resolution 3D electron microscopy to examine the ultrastructure of sexual and asexual blood stages of the malaria parasite, shedding light on its unique cell biology.

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  • Topology and chirality of fermionic quasiparticles have enabled exciting discoveries, including quantum anomalous Hall liquids and topological superconductivity. Recently, topological and chiral phonons emerge as new and fast-evolving research directions. While these concepts are separately developed, they are intimately connected in the context of Weyl phonons. The couplings between chiral and topological phonons with various electronic and magnetic quasiparticles are predicted to give rise to new quantum states and giant magnetism with fundamental and applicational interests, ranging from quantum information science to dark matter detectors.

    • Tiantian Zhang
    • Shuichi Murakami
    • Hu Miao
    CommentOpen Access
  • Malaria vaccine research has progressed significantly, with RTS,S/AS01 and R21/Matrix-M receiving WHO endorsement in 2021 / 2023. These vaccines show promise, but challenges like vaccine adherence, strain variation, and resistance persist, highlighting the need for more effective, broad-reaching interventions.

    • Jack Feehan
    • Magdalena Plebanski
    • Vasso Apostolopoulos
    CommentOpen Access
  • The natural host for avian influenza virus (AIV) is waterfowl. However, certain subtypes have breached species barriers, causing epizootics in many avian and mammalian species with occasional zoonotic infections in humans. The ongoing spread of highly pathogenic avian influenza (HPAI) A(H5N1) poses a significant and growing public health threat. Here, we discuss recent advances in viral detection and characterization technologies and their integration into the diagnostics and surveillance of AIV within a “One Health” framework.

    • Qian Niu
    • Zhiwen Jiang
    • Shuo Su
    CommentOpen Access
  • A recent study by Buonomano et al. reports two important contributions; namely, empirical evidence for prediction error-like responses in single cells, using ex vivo preparations and optogenetics. Second, it foregrounds the role of asymmetric coupling in generating itinerant dynamics required for temporal prediction in neuronal circuits.

    • Karl J. Friston
    CommentOpen Access
  • Biotechnology offers a sustainable route to manufacturing, but closing the loop towards safeguarding biodiversity remains challenging. Here, we explore how partnerships with Indigenous Peoples and Local Communities (IP&LC) can promote an ethical and circular bioeconomy.

    • Maria C. T. Astolfi
    • WarīNkwī Flores
    • Keolu Fox
    CommentOpen Access
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