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Joined 5 months ago
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Cake day: November 26th, 2025

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  • This is cool and disclaimer, I did not watch the whole video but was mostly interested in the quality control.

    There is one big reason such a device is so expensive, as for just about every experiment you need complete confidence in its precision. So a commercial device is built to provide that. This might be “less important” in an academic setting where malfunction will just annoy the postdoc, but gets a bit more important in a commercial setting where money is on the line. I guess that is not the use case for this though.

    I don’t see him do any proper QC though, showing colors looking relatively even and getting pretty gradients is nice, but there can still be considerable variation between plates or wells here that are not visible to the eye.

    I haven’t done any proper calibration myself for a while now, but usually one would use a liquid that has some light absorption that can be measured in a plate reader. So you can get actual experimental numbers for the variation between wells but also plates.

    And if he does that it would probably help a lot to compare it with the commercial device, how close is he to that standard of quality?