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Bi-monthly BDM Issue: Highlighted Articles
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A microneedle substrate-based sutureless engineered cardiac patch for myocardial infarction repair | Bio-Design and Manufacturing | Springer Nature Link
A microneedle substrate-based sutureless engineered cardiac patch for myocardial infarction repair | Bio-Design and Manufacturing | Springer Nature Link
Myocardial infarction (MI) is a challenging condition that results in scar formation on the ventricular wall, causing myocardial damage and ventricular thi
Multilayered microfluidic platform for three-dimensional vascularized organ-on-a-chip applications | Bio-Design and Manufacturing | Springer Nature Link
Multilayered microfluidic platform for three-dimensional vascularized organ-on-a-chip applications | Bio-Design and Manufacturing | Springer Nature Link
The vascular network is integral to the developmental and metabolic processes of various tissues and functions as a systemic circulatory system that also i
Development of novel microtubular ionic actuators for endovascular navigation | Bio-Design and Manufacturing | Springer Nature Link
Development of novel microtubular ionic actuators for endovascular navigation | Bio-Design and Manufacturing | Springer Nature Link
Minimally invasive interventional surgery techniques using guidewire-based catheters are widely adopted to treat vascular diseases. However, commonly used
Pathological quality control chips for tuberculosis | Bio-Design and Manufacturing | Springer Nature Link
Pathological quality control chips for tuberculosis | Bio-Design and Manufacturing | Springer Nature Link
Globally, approximately 10 million new tuberculosis (TB) cases are reported annually. Delayed diagnosis due to low detection rates is the primary cause of
Bone marrow mesenchymal stem cell-loaded HAMA hydrogel within highly bionic nerve guidance conduits for peripheral nerve regeneration - Bio-Design and Manufacturing
Bone marrow mesenchymal stem cell-loaded HAMA hydrogel within highly bionic nerve guidance conduits for peripheral nerve regeneration - Bio-Design and Manufacturing
Nerve guidance conduits (NGCs) effectively support and guide the regeneration of injured nerves. However, traditional NGCs often lack essential growth fact
In vivo 3D dose distribution verification for lung cancer: from rigid-body model to porcine lung - Bio-Design and Manufacturing
In vivo 3D dose distribution verification for lung cancer: from rigid-body model to porcine lung - Bio-Design and Manufacturing
This study introduces a novel concept, biological in vivo three-dimensional (3D) dose distribution verification, aimed at investigating how respiratory mot
Miniature Ni-diamond wheel for drilling and grinding of calcified plaque surrogate in chronic total occlusion treatment | Bio-Design and Manufacturing | Springer Nature Link
Miniature Ni-diamond wheel for drilling and grinding of calcified plaque surrogate in chronic total occlusion treatment | Bio-Design and Manufacturing | Springer Nature Link
Chronic total occlusion (CTO) is a cardiovascular disease in which coronary arteries are completely obstructed by atherosclerotic plaques for more than thr
Bio-inspired magnetic soft robot with dual-modal locomotion for enhanced liquid–air interface navigation | Bio-Design and Manufacturing | Springer Nature Link
Bio-inspired magnetic soft robot with dual-modal locomotion for enhanced liquid–air interface navigation | Bio-Design and Manufacturing | Springer Nature Link
Small-scale magnetic soft robots are promising candidates for minimally invasive medical applications; however, they struggle to achieve efficient locomoti
Multiorgan-on-a-chip: an advanced platform for disease modeling, drug toxicity assessment, and therapeutic screening | Bio-Design and Manufacturing | Springer Nature Link
Multiorgan-on-a-chip: an advanced platform for disease modeling, drug toxicity assessment, and therapeutic screening | Bio-Design and Manufacturing | Springer Nature Link
Multiorgan-on-a-chip (MOoC) systems are advanced microfluidic devices that integrate multiple organ models into a single modular unit, each composed of cel
BDM Bimonthly Issue: 12 Highlighted Articles | Instagram | Linktree
BDM Bimonthly Issue: 12 Highlighted Articles | Instagram | Linktree
Bi-monthly BDM Issue: 12 Articles Highlighted
Research insights and clinical opportunities of functional organoid-based platforms | Bio-Design and Manufacturing | Springer Nature Link
Research insights and clinical opportunities of functional organoid-based platforms | Bio-Design and Manufacturing | Springer Nature Link
Stem cell- or tissue-derived three-dimensional organ-like formations, known as organoids, are emerging as effective tools in biomedicine. Since they may be useful in developing customized therapeutic solutions and efficient drug screening protocols, organoids can deepen our understanding of novel disease mechanisms. In doing so, they can facilitate advancements in drug discovery platforms, pharmacological safety, and clinical trials. This review explores various biomedical applications of organoids, including drug development and disease modeling, and highlights specific tools and analytical techniques that can be employed to investigate organoids and their microenvironments. Finally, we review recent clinical trials and patents related to organoids that show great promise for future clinical translation.
Design of linear pneumatic artificial muscles guided by biomechanics of human skeletal muscle for wearable application: a review - Bio-Design and Manufacturing
Design of linear pneumatic artificial muscles guided by biomechanics of human skeletal muscle for wearable application: a review - Bio-Design and Manufacturing
Pneumatic artificial muscles (PAMs) can generate multimodal movements, e.g., linear contraction/extension, spiral torsion, and bending motions. Among these
Polymeric micelles: “magic bullets” for cancer treatment
Polymeric micelles: “magic bullets” for cancer treatment
Nanocarriers are an efficient drug delivery tool used for cancer treatment. Among various nanocarriers, polymeric micelles (PMs) have garnered attention in
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