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Joined 3 years ago
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Cake day: June 27th, 2023

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  • I’m not sure that’s the best source. I don’t see any links to sources for the progesterone claims, and there’s a bunch of fear mongering regarding doctors and official medical advice. Like

    Don’t give a vial into the hands of a doctor, he’d destroy it. Doctors are jealous.

    and

    Medical professionals routinely make mistakes in both directions: approve crazy people and unnecessarily delay transsexuals who’ll not regret.

    and

    Endos are used to such approach, it keeps them busy and paid. With the only goal to maximize quantity of doctor visits paid by patients or insurance, gangs of American endos write guidelines how to treat transsexuals: with same approach. All the numbers in such guidelines and all the bogeyman stories about side effects of estradiol are bullshit. “Normal range” is from measurements of 90% of healthy people: 5% of lowest and 5% of highest results are discounted. Normal range of estradiol for pregnancy is up to 40000 pg/ml = 147000 pmol/l. In a group of 86 pregnant women estradiol level was up to 75137 pg/ml = 275753 pmol/l: http://cebp.aacrjournals.org/content/12/5/452.figures-only. Pregnant women don’t drop dead from such estradiol level, so you wouldn’t even if your peak reaches 5000 pg/ml. It’s even darker than that: the numbers in guidelines are chosen deliberately low to force transsexuals to pay for more doctor visits to beg for more estradiol. Doctors also recall the mantra in their gospels (textbooks) about estrogens: dosage the less the better, stop as soon as possible. They never realize that this mantra was written in the fear of uterine cancer. And that you haven’t an uterus.

    I appreciate the link to source here at least, but I think the logic is flawed and not the best advice. I totally get assuaging fears of estradiol overdose, but peak estradiol isn’t the same as sustained, long term elevated levels.

    Also, saying there’s no evidence for low dose methods-

    So they claim that it’s allegedly better. Doctors in other countries parrot that. There isn’t any evidence. People repeat doctors’ claims.

    -but then advocating for higher dose with no research evidence seems like hypocrisy to me



  • Yup, I made a bad generalization. My bad, and to be clear I’m not a doctor or anything.

    Some SSRIs may have an interaction with grapefruit. But grapefruit interacts with different medications differently, and it’s not based on the class of medication, it’s med specific.

    e.g. Sertraline (Zoloft) is an SSRI and is listed as having an interaction with grapefruit

    https://en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Eta: thanks for calling that out, I’ve learned some interesting things, for example;

    Ketamine: After drinking 200 mL of grapefruit juice daily for five days, the overall absorption of orally ingested ketamine was increased three-fold compared to the control group in a clinical trial. The peak blood ketamine concentration was increased over two-fold.








  • What legal reasons? They’re not legally bound to only accept cis women, its just one of their own rules. They don’t have to go through the courts, they can change their bylaws to include trans women. Or whatever verbiage they need.

    Unless I’m missing something, they have no legal obligation to keep the same bylaws as an organization. Then there’s no basis for a terf to sue.

    ETA: whoop, missed this part of the article apparently;

    Green said the organisation wanted trans women to remain “part of the WI family” and that from April it would launch new “sisterhood groups”, open to all, which would be “a place where we will recognise transgender women as women and explore what it is to be a woman in the 21st century."

    So if that’s possible, then it seems absurd that the main organization could be at risk of legal action